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Modulation of Morphine-induced Antinociception in Acute and Chronic Opioid Treatment by IbudilastLILIUS, Tuomas O; RAUHALA, Pekka V; KAMBUR, Oleg et al.Anesthesiology (Philadelphia). 2009, Vol 111, Num 6, pp 1356-1364, issn 0003-3022, 9 p.Article

Preparation of azaindolines and benzoyl substituted azaindolines: precursors of triazabenzo[cd]azulen-9-one PDE4 inhibitorsBADLAND, Matthew; DEVILLERS, Ingrid; WRIGGLESWORTH, Roger et al.Tetrahedron letters. 2011, Vol 52, Num 41, issn 0040-4039, 5202, 5292-5296 [6 p.]Article

Effects of Andrographolide on the Pharmacokinetics of Aminophylline and Doxofylline in RatsLI, X. P; ZHANG, C. L; GAO, P et al.Drug research (Stuttgart. 2013. Print). 2013, Vol 63, Num 5, pp 258-262, issn 2194-9379, 5 p.Article

The Role of Phosphodiesterases in Schizophrenia : Therapeutic ImplicationsSIUCIAK, Judith A.CNS drugs. 2008, Vol 22, Num 12, pp 983-993, issn 1172-7047, 11 p.Article

Cilomilast for COPD : Results of a 6-month, placebo-controlled study of a potent, selective inhibitor of phosphodiesterase 4RENNARD, Stephen I; SCHACHTER, Neil; STREK, Mary et al.Chest. 2006, Vol 129, Num 1, pp 56-66, issn 0012-3692, 11 p.Article

Recovery of respiratory activity after C2 hemisection (C2HS): Involvement of adenosinergic mechanismsNANTWI, Kwaku D.Respiratory physiology & neurobiology. 2009, Vol 169, Num 2, pp 102-114, issn 1569-9048, 13 p.Article

Apremilast: First Global ApprovalPOOLE, Raewyn M; BALLANTYNE, Anita D.Drugs (Basel). 2014, Vol 74, Num 7, pp 825-837, issn 0012-6667, 13 p.Article

Efficacy of apremilast in the treatment of moderate to severe psoriasis: a randomised controlled trialPAPP, Kim; CATHER, Jennifer C; ROSOPH, Les et al.Lancet (British edition). 2012, Vol 380, Num 9843, pp 738-746, issn 0140-6736, 9 p.Article

Rhumatisme psoriasique: Résultats de l'ustekinumab et de l'apremilastPACCOU, Julien.Rhumatos. 2012, Vol 9, Num 83, pp 447-450, issn 1771-0081, 4 p.Article

Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+ ) -2 -[4 -({[2 -(benzo[1,3 ]dioxol -5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and humanKALGUTKAR, Amit S; BO FENG; DUIGNAN, David B et al.Drug metabolism and disposition. 2007, Vol 35, Num 11, pp 2111-2118, issn 0090-9556, 8 p.Article

Theophylline inhibits the cough reflex through a novel mechanism of actionDUBUIS, Eric; WORTLEY, Michael A; GRACE, Megan S et al.Journal of allergy and clinical immunology. 2014, Vol 133, Num 6, pp 1588-1598, issn 0091-6749, 11 p.Article

Ibudilast in healthy volunteers : safety, tolerability and pharmacokinetics with single and multiple dosesROLAN, Paul; GIBBONS, Jacqueline A; LIN HE et al.British journal of clinical pharmacology. 2008, Vol 66, Num 6, pp 792-801, issn 0306-5251, 10 p.Article

Calorimetric determination of dissolution enthalpy with a novel flow-through methodLEHTO, Vesa-Pekka; TENHO, Mikko; HÄMÄLÄINEN, Olli-Pekka et al.Journal of pharmaceutical and biomedical analysis. 2010, Vol 53, Num 4, pp 821-825, issn 0731-7085, 5 p.Article

Accelerated Dissolution Testing for Controlled Release Microspheres Using the Flow-Through Dissolution ApparatusCOLLIER, Jarrod W; THAKARE, Mohan; GARNER, Solomon T et al.Pharmaceutical development and technology. 2009, Vol 14, Num 1, pp 9-17, issn 1083-7450, 9 p.Article

Differences in Characteristics of Pellets Prepared by Different Pelletization MethodsHÄRING, Adam; VETCHY, David; JANOVSKA, Lucie et al.Drug development and industrial pharmacy. 2008, Vol 34, Num 3, pp 289-296, issn 0363-9045, 8 p.Article

Low-dose theophylline restores corticosteroid responsiveness in rats with smoke-induced airway inflammationXIANWEN SUN; QINGYUN LI; YI GONG et al.Canadian journal of physiology and pharmacology. 2012, Vol 90, Num 7, pp 895-902, issn 0008-4212, 8 p.Article

Pd-mediated functionalization of polysubstituted pyrroles: Their evaluation as potential inhibitors of PDE4BHASKAR KUMAR, T; SUMANTH, Ch; SHIVA KUMAR, K et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 17, pp 5639-5647, issn 0960-894X, 9 p.Article

Synthesis and Preliminary Characterization of Sulfamethazine-Theophylline Co-CrystalJIE LU; ROWANI, Sohrab.Journal of pharmaceutical sciences. 2010, Vol 99, Num 9, pp 4042-4047, issn 0022-3549, 6 p.Article

Manipulating Theophylline Monohydrate Formation During High-Shear Wet Granulation Through Improved Understanding of the Role of Pharmaceutical ExcipientsWIKSTRÖM, Hakan; CARROLL, William J; TAYLOR, Lynne S et al.Pharmaceutical research. 2008, Vol 25, Num 4, pp 923-935, issn 0724-8741, 13 p.Article

Time-Dependent Effects of Klebsiella Pneumoniae Endotoxin (KPLPS) on the Pharmacokinetics of Theophylline in Rats : Return of the Parameters in 96-Hour KPLPS Rats to the Control LevelsYANG, Kyung H; JUNG, Young S; LEE, Dae Y et al.Drug metabolism and disposition. 2008, Vol 36, Num 5, pp 811-815, issn 0090-9556, 5 p.Article

Effect of decursinol angelate on the pharmacokinetics of theophylline and its metabolites in ratsCHAE, Jung-Woo; AN, Jung-Hwa; KANG, Wonku et al.Food and chemical toxicology. 2012, Vol 50, Num 10, pp 3666-3672, issn 0278-6915, 7 p.Article

A selective phosphodiesterase 4 (PDE4) inhibitor Zl-n-91 suppresses IL-17 production by human memory Th17 cellsRUIHONG MA; YANG, Bin-Yan; WU, Chang-You et al.International immunopharmacology. 2008, Vol 8, Num 10, pp 1408-1417, issn 1567-5769, 10 p.Article

Acceleration of in vitro dissolution studies of sustained release dosage form of theophylline and in vitro-in vivo evaluations in terms of correlationsERTAN, Gökhan; KARASULU, Ercüment; ÖZGÜNEY, Isik et al.European journal of drug metabolism and pharmacokinetics. 2011, Vol 36, Num 4, pp 243-248, issn 0378-7966, 6 p.Article

Aprémilast pour traiter l'arthrite psoriasique = Apremilast for psoriatic arthritisThe Medical letter on drugs and therapeutics (Edition française). 2014, Vol 36, Num 13, pp 53-54, issn 0253-8512, 2 p.Article

Intranasal Theophylline Treatment of Hyposmia and Hypogeusia: A Pilot StudyHENKIN, Robert I; SCHULTZ, Michael; MINNICK-POPPE, Laura et al.Archives of otolaryngology, head & neck surgery. 2012, Vol 138, Num 11, pp 1064-1070, issn 0886-4470, 7 p.Article

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